EC2 experienced outbound connectivity issues from us-west-2. Here is the statement from them:
1:59 PM PDT We are investigating Network Connectivity issues in the US-WEST-2 Region.
2:33 PM PDT Between 1:46 PM and 2:15 PM PDT we experienced network connectivity issues in the US-WEST-2 Region. The issue has been resolved and the service is operating normally.
Our portal cluster exists in us-west-2 and portal schedules to all regions through us-west-1. Due to the above connectivity issues the portal cluster could not reach out to transpile an schedule against us-west-1. Once the networking was fixed the issue went away. As an aside, we also performed an upgrade to our underlying transpilation service to ensure they were not getting OOM kills and causing the problem however this proved to be a red herring.